Norco 10-325 mg is a combination of two medications used to manage pain when non-opioid medications aren’t working well enough, as both of the drugs in the combination may affect you differently. These drugs work in the human brain to block pain signals and help to decrease the ability to feel pain. However, this medication is a controlled substance so there is a high risk of misuse and dependency. The Norco drug is available in three strengths: 5-325 mg, 7.5-325 mg, and 10-325 mg. The pill with the imprint “NORCO 539” is yellow oval-shaped and has been identified as Norco 10-325 mg that is supplied by Allergan, Inc. The initial dosage is 1 pill every 4 to 6 hours as needed and within 30 minutes, it will start relieving pain. In addition, do not exceed more than 6 tablets per day. While taking Norco 10-325 mg, it is recommended to drink enough water each day and at the same time, you should avoid drinking alcohol. This drug can cause side effects and symptoms like drowsiness, dizziness or lightheaded, nausea, vomiting, constipation, skin rash, trouble breathing, drug dependence, etc.