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Lortab is a prescription drug that combines two active ingredients: hydrocodone and acetaminophen. It is used for temporary relief of moderate to severe pain. Hydrocodone is an opioid analgesic, whereas acetaminophen is a non-opioid analgesic and antipyretic. Together they work synergistically to provide effective pain relief. Hydrocodone, the opioid component of Lortab, acts on opioid receptors in the brain and spinal cord, reducing the perception of pain. It also helps prevent inflammation by suppressing inflammation. Hydrocodone is classified as a Schedule II controlled substance due to its potential for abuse and dependence. It is important to use Lortab only under the supervision of a healthcare professional and as prescribed. Another ingredient in Lortab, acetaminophen, helps enhance the pain-relieving effects of hydrocodone. It works by blocking prostaglandins, substances that cause pain and inflammation. Acetaminophen also helps reduce fever by activating the hypothalamic thermoregulatory center in the brain. Lortab is often prescribed for pain management after surgery, dental treatment, or injury. It can also be used for chronic pain conditions when other non-opioid pain medications are ineffective. Lortab dosing is done based on each person’s pain intensity, medical history, and response to the drug.